» » »

Taxol Boosts Odds of Chronic Pain Boston MA

The chemotherapy drug paclitaxel (Taxol) increases the risk of chronic neuropathic pain in breast cancer survivors, a new study shows. It included 240 women who took part in clinical trials of Taxol between 1994 and 2001. Those who experienced chemotherapy-induced peripheral neuropathy during their treatment with Taxol were three times more likely to eventually be diagnosed with chronic neuropathic pain.

Ajay D Wasan, MD
(617) 732-8510
75 Francis St
Boston, MA
Business
Brigham & Women's Hospital Anesthesiology
Specialties
Anesthesiology

Data Provided by:
Carl Elliott Rosow, MD
(617) 726-8812
55 Fruit St
Boston, MA
Specialties
Anesthesiology
Gender
Male
Education
Medical School: Boston Univ Sch Of Med, Boston Ma 02118
Graduation Year: 1973

Data Provided by:
Mohammed Iqbal Ahmed
(617) 636-5000
750 Washington St
Boston, MA
Specialty
Anesthesiology

Data Provided by:
David W Krivan, MD
(617) 789-2777
12 Melrose St Apt 5
Boston, MA
Specialties
Anesthesiology
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Lisa Warren
(617) 726-8590
55 Fruit St
Boston, MA
Specialty
Anesthesiology

Data Provided by:
Marissa S Lowenthal, MD
259 W Newton St Apt 6
Boston, MA
Specialties
Anesthesiology
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Jan Fredrik Hesselvik, MD
(617) 638-6973
88 E Newton St
Boston, MA
Specialties
Anesthesiology
Gender
Male
Education
Medical School: Univ I Linkoping, Med Fak, Linkoping, Sweden
Graduation Year: 1978

Data Provided by:
Paul G Firth
(617) 726-3030
55 Fruit St
Boston, MA
Specialty
Anesthesiology

Data Provided by:
Rachel Castle, MD
55 Fruit St
Boston, MA
Specialties
Anesthesiology
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Andrew Park Kim, MD
55 Fruit St
Boston, MA
Specialties
Anesthesiology
Gender
Male
Education
Medical School: Boston Univ Sch Of Med, Boston Ma 02118
Graduation Year: 2000

Data Provided by:
Data Provided by:

Taxol Boosts Odds of Chronic Pain

Provided By:

MONDAY, Nov. 30 (HealthDay News) -- The chemotherapy drug paclitaxel (Taxol) increases the risk of chronic neuropathic pain in breast cancer survivors, a new study shows.

It included 240 women who took part in clinical trials of Taxol between 1994 and 2001. Those who experienced chemotherapy-induced peripheral neuropathy during their treatment with Taxol were three times more likely to eventually be diagnosed with chronic neuropathic pain.

The study is published in the November issue of the Journal of Pain.

The findings indicate that patients treated with Taxol should be regularly monitored for neuropathic pain after their chemotherapy ends, said the researchers from the University of Texas M.D. Anderson Cancer Center.

In certain cases, patients and doctors should review the risks and benefits for continuing treatment with Taxol if a patient is likely to experience worsening neuropathy, the study authors added.

They noted that the same cellular mechanism that's altered by Taxol to kill tumors can be toxic to normal tissue.

More information

The National Pain Foundation has more about neuropathic pain.

SOURCE: American Pain Society, news release, Nov. 23, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com